6VBI: crystal structure of PDE5 in complex with a non-competitive inhibitor

PDB ID: 6VBIDownload
MMDB ID: 197653
PDB Deposition Date: 2019/12/18
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.30001  Å
Source Organism:
Similar Structures:
Biological Unit for 6VBI: monomeric; determined by author
Molecular Components in 6VBI
Label Count Molecule
Protein (1 molecule)
1
Cgmp-specific 3',5'-cyclic Phosphodiesterase
(Gene symbol: PDE5A)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(13bS)-4,9-dimethoxy-14-methyl-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one(13bS)-4,9-dimethoxy-14-methyl-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303