6V9C: Crystal structure of FGFR4 kinase domain in complex with covalent inhibitor

PDB ID: 6V9CDownload
MMDB ID: 185756
PDB Deposition Date: 2019/12/13
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 6V9C: monomeric; determined by author and by software (PISA)
Molecular Components in 6V9C
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 4
(Gene symbol: FGFR4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-[(3R,4S)-4-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}oxolan-3-yl]prop-2-enamideN-[(3R,4S)-4-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}oxolan-3-yl]prop-2-enamide
2
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303