6UZ8: Cryo-EM structure of human TRPC6 in complex with agonist AM-0883

PDB ID: 6UZ8Download
MMDB ID: 185439
PDB Deposition Date: 2019/11/14
Updated in MMDB: 2020/03
Experimental Method:
electron microscopy
Resolution: 2.84  Å
Source Organism:
Similar Structures:
Biological Unit for 6UZ8: tetrameric; determined by author
Molecular Components in 6UZ8
Label Count Molecule
Proteins (4 molecules)
4
Short Transient Receptor Potential Channel 6
(Gene symbol: TRPC6)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
4
2-[[(2~{S})-2-decanoyloxy-3-dodecanoyloxy-propoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium2-[[(2~{S})-2-decanoyloxy-3-dodecanoyloxy-propoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium
2
8
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
3
4
(5-chloro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)[(2R)-2,3-dihydro-1,4-benzodioxin-2-yl]methanone(5-chloro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)[(2R)-2,3-dihydro-1,4-benzodioxin-2-yl]methanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303