6UXE: Structure of the human mitochondrial desulfurase complex Nfs1-ISCU2(M140I)-ISD11 with E.coli ACP1 at 1.57 A resolution showing flexibility of N terminal end of ISCU2

PDB ID: 6UXEDownload
MMDB ID: 181592
PDB Deposition Date: 2019/11/7
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 1.57  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 6UXE: octameric; determined by author and by software (PISA)
Molecular Components in 6UXE
Label Count Molecule
Proteins (8 molecules)
2
Cysteine Desulfurase, Mitochondrial
Molecule annotation
2
LYR Motif-containing Protein 4
Molecule annotation
2
Acyl Carrier Protein
Molecule annotation
2
Iron-sulfur Cluster Assembly Enzyme Iscu, Mitochondrial
Molecule annotation
Chemicals and Non-standard biopolymers (156 molecules)
1
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
2
12
GLYCEROLGLYCEROL
3
98
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
22
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
4
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
6
2
2,5,8,11,14,17-HEXAOXANONADECAN-19-OL2,5,8,11,14,17-HEXAOXANONADECAN-19-OL
7
2
2,3-DIHYDROXY-1,4-DITHIOBUTANE2,3-DIHYDROXY-1,4-DITHIOBUTANE
8
6
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
9
2
{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID
10
2
S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioateS-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate
11
2
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
12
2
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303