6UX0: Isavuconazole bound complex of Acanthamoeba castellanii CYP51

PDB ID: 6UX0Download
MMDB ID: 193924
PDB Deposition Date: 2019/11/6
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.93  Å
Source Organism:
Similar Structures:
Biological Unit for 6UX0: trimeric; determined by author
Molecular Components in 6UX0
Label Count Molecule
Proteins (3 molecules)
3
Obtusifoliol 14alphademethylase
(Gene symbol: ACA1_372720)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
3
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
3
4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile
3
1
FE (III) IONFE (III) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303