6UWX: Cocrystal of BRD4(D1) with a ethyl carbamate thiazepane inhibitor

PDB ID: 6UWXDownload
MMDB ID: 182825
PDB Deposition Date: 2019/11/5
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.307  Å
Source Organism:
Similar Structures:
Biological Unit for 6UWX: monomeric; determined by author and by software (PISA)
Molecular Components in 6UWX
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
ethyl (7S)-7-(thiophen-2-yl)-1,4-thiazepane-4-carboxylateethyl (7S)-7-(thiophen-2-yl)-1,4-thiazepane-4-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303