6UWW: Crystal structure of dihydrofolate reductase from Mycobacterium ulcerans with P218 inhibitor

PDB ID: 6UWWDownload
MMDB ID: 195049
PDB Deposition Date: 2019/11/5
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 0.92  Å
Source Organism:
Similar Structures:
Biological Unit for 6UWW: monomeric; determined by author and by software (PISA)
Molecular Components in 6UWW
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid
2
2
SULFATE IONSULFATE ION
3
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303