6UON: Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation

PDB ID: 6UONDownload
MMDB ID: 188037
PDB Deposition Date: 2019/10/15
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Molecular Components in 6UON
Label Count Molecule
Proteins (10 molecules)
2
Tcr-v-alpha-12-02*01
Molecule annotation
2
Tcr-v-beta-10-2*01
Molecule annotation
2
HLA Class I Antigen
(Gene symbol: HLA-C)
Molecule annotation
2
Beta-2-microglobulin
(Gene symbol: B2M)
Molecule annotation
2
Gly-ala-asp-gly-val-gly-lys-ser-ala-leu
(Gene symbol: NRAS)
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303