6UNJ: Human CYP3A4 bound to an inhibitor

PDB ID: 6UNJDownload
MMDB ID: 183937
PDB Deposition Date: 2019/10/12
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 6UNJ: trimeric; determined by author
Molecular Components in 6UNJ
Label Count Molecule
Proteins (3 molecules)
3
Cytochrome P450 3A4
(Gene symbol: CYP3A4)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
3
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
3
tert-butyl [(2R)-1-(naphthalen-1-yl)-3-{[(2S)-1-oxo-3-phenyl-1-{[2-(pyridin-3-yl)ethyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamatetert-butyl [(2R)-1-(naphthalen-1-yl)-3-{[(2S)-1-oxo-3-phenyl-1-{[2-(pyridin-3-yl)ethyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303