6UMF: Crystal structure of human GAC in complex with inhibitor UPGL00012

PDB ID: 6UMFDownload
MMDB ID: 194156
PDB Deposition Date: 2019/10/9
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.68  Å
Source Organism:
Similar Structures:
Biological Unit for 6UMF: tetrameric; determined by author and by software (PISA)
Molecular Components in 6UMF
Label Count Molecule
Proteins (4 molecules)
4
Glutaminase Kidney Isoform, Mitochondrial
(Gene symbol: GLS)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-(5-{[1-(5-amino-1,3,4-thiadiazol-2-yl)piperidin-4-yl]oxy}-1,3,4-thiadiazol-2-yl)-2-phenylacetamideN-(5-{[1-(5-amino-1,3,4-thiadiazol-2-yl)piperidin-4-yl]oxy}-1,3,4-thiadiazol-2-yl)-2-phenylacetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303