6ULN: Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation

PDB ID: 6ULNDownload
MMDB ID: 188033
PDB Deposition Date: 2019/10/8
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.01  Å
Source Organism:
Similar Structures:
Biological Unit for 6ULN: heptameric; determined by author
Molecular Components in 6ULN
Label Count Molecule
Proteins (7 molecules)
1
HLA Class I Antigen
(Gene symbol: HLA-C)
Molecule annotation
1
Beta-2-microglobulin
(Gene symbol: B2M)
Molecule annotation
1
Gly-ala-asp-gly-val-gly-lys-ser-ala
(Gene symbol: NRAS)
Molecule annotation
2
Tcr-v-alpha-4*01
Molecule annotation
2
Tcr-v-beta-5-6*01
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
3
SULFATE IONSULFATE ION
2
8
GLYCEROLGLYCEROL
3
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303