6UKB: Crystal structure of human GAC in complex with inhibitor UPGL00012

PDB ID: 6UKBDownload
MMDB ID: 193652
PDB Deposition Date: 2019/10/4
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 6UKB: tetrameric; determined by author and by software (PISA)
Molecular Components in 6UKB
Label Count Molecule
Proteins (4 molecules)
4
Glutaminase Kidney Isoform, Mitochondrial
(Gene symbol: GLS)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-[5-(4-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]oxy}piperidin-1-yl)-1,3,4-thiadiazol-2-yl]acetamideN-[5-(4-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]oxy}piperidin-1-yl)-1,3,4-thiadiazol-2-yl]acetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303