6UF0: Crystal structure of N-(4-((4-methoxy-N-(2,2,2-trifluoroethyl)phenyl)sulfonamido)isoquinolin-1-yl)-N-((4-methoxyphenyl)sulfonyl)glycine bound to human Keap1 Kelch domain

PDB ID: 6UF0Download
MMDB ID: 182447
PDB Deposition Date: 2019/9/23
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.96  Å
Source Organism:
Similar Structures:
Biological Unit for 6UF0: monomeric; determined by author
Molecular Components in 6UF0
Label Count Molecule
Protein (1 molecule)
1
Kelch-like Ech-associated Protein 1
(Gene symbol: KEAP1)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
N-[(4-methoxyphenyl)sulfonyl]-N-(4-{[(4-methoxyphenyl)sulfonyl](2,2,2-trifluoroethyl)amino}isoquinolin-1-yl)glycineN-[(4-methoxyphenyl)sulfonyl]-N-(4-{[(4-methoxyphenyl)sulfonyl](2,2,2-trifluoroethyl)amino}isoquinolin-1-yl)glycine
2
6
FORMIC ACIDFORMIC ACID
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303