6UAP: Crystal structure of tryptophan synthase from M. tuberculosis - open form with BRD6309 bound

PDB ID: 6UAPDownload
MMDB ID: 180944
PDB Deposition Date: 2019/9/11
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.745  Å
Source Organism:
Similar Structures:
Biological Unit for 6UAP: tetrameric; determined by author and by software (PISA)
Molecular Components in 6UAP
Label Count Molecule
Proteins (4 molecules)
2
Tryptophan Synthase Alpha Chain
(Gene symbol: trpA)
Molecule annotation
2
Tryptophan Synthase Beta Chain
(Gene symbol: trpB)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
10
FORMIC ACIDFORMIC ACID
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
(2R,3S,4R)-3-(4'-chloro-2',6'-difluoro[1,1'-biphenyl]-4-yl)-4-(fluoromethyl)azetidine-2-carbonitrile(2R,3S,4R)-3-(4'-chloro-2',6'-difluoro[1,1'-biphenyl]-4-yl)-4-(fluoromethyl)azetidine-2-carbonitrile
4
1
MALONIC ACIDMALONIC ACID
5
2
D-MALATED-MALATE
6
2
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303