6UAJ: Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Free canonical octamer reconstruction

PDB ID: 6UAJDownload
MMDB ID: 185741
PDB Deposition Date: 2019/9/10
Updated in MMDB: 2025/06
Experimental Method:
electron microscopy
Resolution: 3.84  Å
Source Organism:
Similar Structures:
Biological Unit for 6UAJ: octameric; determined by author
Molecular Components in 6UAJ
Label Count Molecule
Proteins (8 molecules)
8
Inosine-5'-monophosphate Dehydrogenase 2
(Gene symbol: IMPDH2)
Molecule annotation
Chemicals and Non-standard biopolymers (40 molecules)
1
16
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
8
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
3
8
INOSINIC ACIDINOSINIC ACID
4
8
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303