6U9O: Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Fully compressed filament segment reconstruction

PDB ID: 6U9ODownload
MMDB ID: 185737
PDB Deposition Date: 2019/9/9
Updated in MMDB: 2025/05
Experimental Method:
electron microscopy
Resolution: 3.36  Å
Source Organism:
Similar Structures:
Biological Unit for 6U9O: hexadecameric; determined by author
Molecular Components in 6U9O
Label Count Molecule
Proteins (16 molecules)
16
Inosine-5'-monophosphate Dehydrogenase 2
(Gene symbol: IMPDH2)
Molecule annotation
Chemicals and Non-standard biopolymers (40 molecules)
1
16
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
8
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
3
8
INOSINIC ACIDINOSINIC ACID
4
8
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303