6U8B: Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction

PDB ID: 6U8BDownload
MMDB ID: 181998
PDB Deposition Date: 2019/9/4
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.261  Å
Source Organism:
Similar Structures:
Biological Unit for 6U8B: monomeric; determined by author and by software (PISA)
Molecular Components in 6U8B
Label Count Molecule
Protein (1 molecule)
1
WD Repeat-containing Protein 5
(Gene symbol: WDR5)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
3-{[(5-bromo-2-methoxyphenyl)sulfonyl]amino}-5-chloro-2-hydroxybenzoic acid3-{[(5-bromo-2-methoxyphenyl)sulfonyl]amino}-5-chloro-2-hydroxybenzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303