6U7C: Human GRK2 in complex with Gbetagamma subunits and CCG258747

PDB ID: 6U7CDownload
MMDB ID: 186463
PDB Deposition Date: 2019/9/2
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.44  Å
Source Organism:
Bos taurus▼
Similar Structures:
Biological Unit for 6U7C: trimeric; determined by author and by software (PISA)
Molecular Components in 6U7C
Label Count Molecule
Proteins (3 molecules)
1
Beta-adrenergic Receptor Kinase 1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
5-[(3S,4R)-3-{[(2H-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluoro-N-[(2H-indazol-3-yl)methyl]benzamide5-[(3S,4R)-3-{[(2H-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluoro-N-[(2H-indazol-3-yl)methyl]benzamide
2
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303