6U37: Structure of VX-phosphonylated hAChE in complex with oxime reactivator RS194B

PDB ID: 6U37Download
MMDB ID: 184162
PDB Deposition Date: 2019/8/21
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 6U37: trimeric; determined by author and by software (PISA)
Molecular Components in 6U37
Label Count Molecule
Proteins (3 molecules)
3
Acetylcholinesterase
(Gene symbol: ACHE)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
3
O-ETHYLMETHYLPHOSPHONIC ACID ESTER GROUPO-ETHYLMETHYLPHOSPHONIC ACID ESTER GROUP
2
3
(2E)-N-[2-(azepan-1-yl)ethyl]-2-(hydroxyimino)acetamide(2E)-N-[2-(azepan-1-yl)ethyl]-2-(hydroxyimino)acetamide
3
6
GLYCEROLGLYCEROL
4
3
NITRATE IONNITRATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303