6U2P: PCSK9 in complex with compound 5

PDB ID: 6U2PDownload
MMDB ID: 181161
PDB Deposition Date: 2019/8/20
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 2.04  Å
Source Organism:
Similar Structures:
Biological Unit for 6U2P: dimeric; determined by author and by software (PISA)
Molecular Components in 6U2P
Label Count Molecule
Proteins (2 molecules)
2
Proprotein Convertase Subtilisin/kexin Type 9
(Gene symbol: PCSK9)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
2-fluoro-4-{[(1R)-6-methoxy-1-methyl-1-{2-oxo-2-[(1,3-thiazol-2-yl)amino]ethyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}benzoic acid2-fluoro-4-{[(1R)-6-methoxy-1-methyl-1-{2-oxo-2-[(1,3-thiazol-2-yl)amino]ethyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303