6U18: Directed evolution of a biosensor selective for the macrolide antibiotic clarithromycin

PDB ID: 6U18Download
MMDB ID: 191382
PDB Deposition Date: 2019/8/15
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 6U18: dimeric; determined by author and by software (PISA)
Molecular Components in 6U18
Label Count Molecule
Proteins (2 molecules)
2
Erythromycin Resistance Repressor Protein
(Gene symbol: mphR)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CLARITHROMYCINCLARITHROMYCIN
2
1
CITRATE ANIONCITRATE ANION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303