6U06: Discovery of Lysine-Targeted eIF4E Inhibitors through Covalent Docking

PDB ID: 6U06Download
MMDB ID: 180563
PDB Deposition Date: 2019/8/13
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.96  Å
Source Organism:
Similar Structures:
Biological Unit for 6U06: monomeric; determined by author
Molecular Components in 6U06
Label Count Molecule
Protein (1 molecule)
1
Eukaryotic Translation Initiation Factor 4E
(Gene symbol: Eif4e)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-{[(4-cyanophenyl)methyl](1-oxo-1,2-dihydroisoquinolin-7-yl)sulfamoyl}benzene-1-sulfonyl fluoride3-{[(4-cyanophenyl)methyl](1-oxo-1,2-dihydroisoquinolin-7-yl)sulfamoyl}benzene-1-sulfonyl fluoride
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303