6TZ7: Crystal Structure of Aspergillus fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus)

PDB ID: 6TZ7Download
MMDB ID: 179701
PDB Deposition Date: 2019/8/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6TZ7: trimeric; determined by author and by software (PISA)
Molecular Components in 6TZ7
Label Count Molecule
Proteins (3 molecules)
1
Serine/threonine-protein Phosphatase 2B Catalytic Subunit
(Gene symbol: AFUA_5G09360)
Molecule annotation
1
Calcineurin Ca2+-binding Regulatory Subunit Cnab
(Gene symbol: AFUA_6G04540)
Molecule annotation
1
Fk506-binding Protein 1A
(Gene symbol: AFUA_6G12170)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
ZINC IONZINC ION
2
1
FE (III) IONFE (III) ION
3
1
PHOSPHATE IONPHOSPHATE ION
4
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
3
CALCIUM IONCALCIUM ION
6
1
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303