6TXE: Crystal structure of tetrameric human wt-SAMHD1 (residues 109-626) with GTP, dATP, dTMPNPP and Mg

PDB ID: 6TXEDownload
MMDB ID: 189244
PDB Deposition Date: 2020/1/14
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 3.19  Å
Source Organism:
Similar Structures:
Biological Unit for 6TXE: tetrameric; determined by author and by software (PISA)
Molecular Components in 6TXE
Label Count Molecule
Proteins (4 molecules)
4
Deoxynucleoside Triphosphate Triphosphohydrolase Samhd1
(Gene symbol: SAMHD1)
Molecule annotation
Chemicals and Non-standard biopolymers (27 molecules)
1
4
FE (III) IONFE (III) ION
2
8
MAGNESIUM IONMAGNESIUM ION
3
4
5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine
4
4
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
5
4
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
6
3
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303