6TX3: HPF1 bound to catalytic fragment of PARP2

PDB ID: 6TX3Download
MMDB ID: 184457
PDB Deposition Date: 2020/1/13
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.96  Å
Source Organism:
Similar Structures:
Biological Unit for 6TX3: dimeric; determined by author and by software (PISA)
Molecular Components in 6TX3
Label Count Molecule
Proteins (2 molecules)
1
Poly [adp-ribose] Polymerase 2,poly [adp-ribose] Polymerase 2
(Gene symbol: PARP2)
Molecule annotation
1
Histone Parylation Factor 1
(Gene symbol: HPF1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303