6TW5: Plasmodium vivax N-myristoyltransferase with bound indazole inhibitor IMP-917

PDB ID: 6TW5Download
MMDB ID: 204621
PDB Deposition Date: 2020/1/12
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 6TW5: monomeric; determined by author
Molecular Components in 6TW5
Label Count Molecule
Protein (1 molecule)
1
Glycylpeptide N-tetradecanoyltransferase
(Gene symbol: PVX_085815)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine
2
1
TETRADECANOYL-COATETRADECANOYL-COA
3
1
MAGNESIUM IONMAGNESIUM ION
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
CHLORIDE IONCHLORIDE ION
6
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303