6TT0: Crystal structure of a potent and reversible dual binding site Acetylcholinesterase chiral inhibitor

PDB ID: 6TT0Download
MMDB ID: 188751
PDB Deposition Date: 2019/12/22
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.80003  Å
Source Organism:
Similar Structures:
Biological Unit for 6TT0: dimeric; determined by author
Molecular Components in 6TT0
Label Count Molecule
Proteins (2 molecules)
2
Acetylcholinesterase
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
(1~{R},3~{S})-~{N}-(6,7-dimethoxy-2-oxidanylidene-chromen-3-yl)-3-[(phenylmethyl)amino]cyclohexane-1-carboxamide(1~{R},3~{S})-~{N}-(6,7-dimethoxy-2-oxidanylidene-chromen-3-yl)-3-[(phenylmethyl)amino]cyclohexane-1-carboxamide
2
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303