6TPN: Crystal structure of the Orexin-2 receptor in complex with HTL6641 at 2.61 A resolution

PDB ID: 6TPNDownload
MMDB ID: 182799
PDB Deposition Date: 2019/12/13
Updated in MMDB: 2020/03
Experimental Method:
x-ray diffraction
Resolution: 2.608  Å
Source Organism:
Similar Structures:
Biological Unit for 6TPN: monomeric; determined by author and by software (PISA)
Molecular Components in 6TPN
Label Count Molecule
Protein (1 molecule)
1
Orexin Receptor Type 2,glga Glycogen Synthase,orexin Receptor Type 2
(Gene symbol: HCRTR2)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
2-(5,6-dimethoxypyridin-3-yl)-1,1-bis(oxidanylidene)-4-[[2,4,6-tris(fluoranyl)phenyl]methyl]pyrido[2,3-e][1,2,4]thiadiazin-3-one2-(5,6-dimethoxypyridin-3-yl)-1,1-bis(oxidanylidene)-4-[[2,4,6-tris(fluoranyl)phenyl]methyl]pyrido[2,3-e][1,2,4]thiadiazin-3-one
2
2
NITRATE IONNITRATE ION
3
2
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
4
4
OLEIC ACIDOLEIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303