6TN8: Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound BI-9564

PDB ID: 6TN8Download
MMDB ID: 182434
PDB Deposition Date: 2019/12/6
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.63  Å
Source Organism:
Similar Structures:
Biological Unit for 6TN8: monomeric; determined by author and by software (PISA)
Molecular Components in 6TN8
Label Count Molecule
Protein (1 molecule)
1
Activin Receptor Type I
(Gene symbol: ACVR1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
1,4-DIETHYLENE DIOXIDE1,4-DIETHYLENE DIOXIDE
2
1
4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one
3
2
SULFATE IONSULFATE ION
4
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303