6TMO: Structure determination of an enhanced affinity TCR, a24b17, in complex with HLA-A*02:01 presenting a MART-1 peptide, EAAGIGILTV

PDB ID: 6TMODownload
MMDB ID: 193637
PDB Deposition Date: 2019/12/5
Updated in MMDB: 2020/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6TMO: pentameric; determined by author and by software (PISA)
Molecular Components in 6TMO
Label Count Molecule
Proteins (5 molecules)
1
MHC Class I Antigen
(Gene symbol: HLA-A)
Molecule annotation
1
Beta-2-microglobulin
(Gene symbol: B2M)
Molecule annotation
1
Eaagigiltv
Molecule annotation
1
Alpha Chain of Engineered High Affinity T-cell Receptor
Molecule annotation
1
Beta Chain of High Affinity Engineered T-cell Receptor
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
5
GLYCEROLGLYCEROL
2
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
5
SULFATE IONSULFATE ION
4
3
TRIS(HYDROXYETHYL)AMINOMETHANETRIS(HYDROXYETHYL)AMINOMETHANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303