6TMC: VIM-2_1dh-Triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-beta-lactamases

PDB ID: 6TMCDownload
MMDB ID: 190395
PDB Deposition Date: 2019/12/4
Updated in MMDB: 2020/09
Experimental Method:
x-ray diffraction
Resolution: 1.4  Å
Source Organism:
Similar Structures:
Biological Unit for 6TMC: monomeric; determined by author and by software (PISA)
Molecular Components in 6TMC
Label Count Molecule
Protein (1 molecule)
1
Beta-lactamase Class B Vim-2
(Gene symbol: blaVIM-2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
4-[2-(phenylsulfonyl)ethyl]-5-(propan-2-yloxymethyl)-1~{H}-1,2,3-triazole4-[2-(phenylsulfonyl)ethyl]-5-(propan-2-yloxymethyl)-1~{H}-1,2,3-triazole
2
2
ZINC IONZINC ION
3
1
HYDROXIDE IONHYDROXIDE ION
4
1
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303