6TMB: VIM-2_1di-Triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-beta-lactamases

PDB ID: 6TMBDownload
MMDB ID: 191893
PDB Deposition Date: 2019/12/4
Updated in MMDB: 2020/09
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6TMB: monomeric; determined by author
Molecular Components in 6TMB
Label Count Molecule
Protein (1 molecule)
1
Beta-lactamase Class B Vim-2
(Gene symbol: blaVIM-2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
3
ZINC IONZINC ION
2
1
HYDROXIDE IONHYDROXIDE ION
3
2
CHLORIDE IONCHLORIDE ION
4
1
~{N}-[[5-[[(phenylmethyl)amino]methyl]-1~{H}-1,2,3-triazol-4-yl]methyl]benzenesulfonamide~{N}-[[5-[[(phenylmethyl)amino]methyl]-1~{H}-1,2,3-triazol-4-yl]methyl]benzenesulfonamide
5
1
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303