6TKS: Tankyrase 2 in complex with an inhibitor (OM-1720)

PDB ID: 6TKSDownload
MMDB ID: 192775
PDB Deposition Date: 2019/11/28
Updated in MMDB: 2021/02
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6TKS: monomeric; determined by author
Molecular Components in 6TKS
Label Count Molecule
Protein (1 molecule)
1
Tankyrase-2
(Gene symbol: TNKS2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
~{N}-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]-1,6-naphthyridine-2-carboxamide~{N}-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]-1,6-naphthyridine-2-carboxamide
2
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303