6THV: X-ray structure of the Danio rerio histone deacetylase 6 (HDAC6; catalytic domain 2) in complex with Tubastatin A

PDB ID: 6THVDownload
MMDB ID: 190102
PDB Deposition Date: 2019/11/21
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 1.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6THV: monomeric; determined by software (PISA)
Molecular Components in 6THV
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 6
(Gene symbol: hdac6)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
1
ZINC IONZINC ION
2
3
POTASSIUM IONPOTASSIUM ION
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
2
THIOCYANATE IONTHIOCYANATE ION
6
1
SODIUM IONSODIUM ION
7
1
GLYCEROLGLYCEROL
8
1
4-[(2-methyl-3,4-dihydro-1~{H}-pyrido[4,3-b]indol-5-yl)methyl]-~{N}-oxidanyl-benzamide4-[(2-methyl-3,4-dihydro-1~{H}-pyrido[4,3-b]indol-5-yl)methyl]-~{N}-oxidanyl-benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303