6TGW: Crystal structure of human Aldehyde dehydrogenase 1A3 in complex with a selective inhibitor

PDB ID: 6TGWDownload
MMDB ID: 202552
PDB Deposition Date: 2019/11/18
Updated in MMDB: 2022/06
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 6TGW: tetrameric; determined by author and by software (PISA)
Molecular Components in 6TGW
Label Count Molecule
Proteins (4 molecules)
4
Aldehyde Dehydrogenase Family 1 Member A3
(Gene symbol: ALDH1A3)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
4
methyl 5-(1,3-benzodioxol-5-yl)-2-phenyl-pyrazolo[1,5-a]pyrimidine-7-carboxylatemethyl 5-(1,3-benzodioxol-5-yl)-2-phenyl-pyrazolo[1,5-a]pyrimidine-7-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303