6TD5: Leishmania tarentolae proteasome 20S subunit complexed with LXE408 and bortezomib

PDB ID: 6TD5Download
MMDB ID: 191674
PDB Deposition Date: 2019/11/7
Updated in MMDB: 2025/12
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6TD5: 28-meric; determined by author and by software (PISA)
Molecular Components in 6TD5
Label Count Molecule
Proteins (28 molecules)
2
Proteasome Subunit Alpha Type
Molecule annotation
2
Proteasome Subunit Alpha Type
Molecule annotation
2
Proteasome Subunit Alpha Type
Molecule annotation
2
Proteasome Endopeptidase Complex
Molecule annotation
2
Proteasome Subunit Alpha Type
Molecule annotation
2
Proteasome Subunit Alpha Type
Molecule annotation
2
Proteasome Endopeptidase Complex
Molecule annotation
2
Proteasome Subunit Beta
Molecule annotation
2
Proteasome Subunit Beta
Molecule annotation
2
Proteasome Subunit Beta
Molecule annotation
2
Proteasome Subunit Family Protein
Molecule annotation
2
Proteasome Subunit Beta
Molecule annotation
2
Proteasome Subunit Beta
Molecule annotation
2
Proteasome Subunit Beta
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
6
N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDEN-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE
2
2
~{N}-[4-fluoranyl-3-[6-(3-methylpyridin-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]phenyl]-2,4-dimethyl-1,3-oxazole-5-carboxamide~{N}-[4-fluoranyl-3-[6-(3-methylpyridin-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]phenyl]-2,4-dimethyl-1,3-oxazole-5-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303