6TD3: Structure of DDB1 bound to CR8-engaged CDK12-cyclinK

PDB ID: 6TD3Download
MMDB ID: 189020
PDB Deposition Date: 2019/11/7
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 3.46  Å
Source Organism:
Similar Structures:
Biological Unit for 6TD3: trimeric; determined by author and by software (PISA)
Molecular Components in 6TD3
Label Count Molecule
Proteins (3 molecules)
1
DNA Damage-binding Protein 1
(Gene symbol: DDB1)
Molecule annotation
1
Cyclin-dependent Kinase 12
(Gene symbol: CDK12)
Molecule annotation
1
Cyclin-k
(Gene symbol: CCNK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303