6T8A: Thrombin in complex with diphenyl ((4-carbamimidoylphenyl)((S)-1-((R)-3-cyclohexyl 2-((phenylmethyl)sulfonamido)propanoyl)pyrrolidine-2-carboxamido)methyl)phosphonate (MI-492)

PDB ID: 6T8ADownload
MMDB ID: 194628
PDB Deposition Date: 2019/10/24
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 1.62  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 6T8A: trimeric; determined by software (PISA)
Molecular Components in 6T8A
Label Count Molecule
Proteins (3 molecules)
1
Prothrombin
Molecule annotation
1
Prothrombin
Molecule annotation
1
Hirudin Variant-2
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
[(~{R})-(4-carbamimidoylphenyl)-[[(2~{S})-1-[(2~{R})-3-cyclohexyl-2-[(phenylmethyl)sulfonylamino]propanoyl]pyrrolidin-2-yl]carbonylamino]methyl]-phenoxy-phosphinous acid[(~{R})-(4-carbamimidoylphenyl)-[[(2~{S})-1-[(2~{R})-3-cyclohexyl-2-[(phenylmethyl)sulfonylamino]propanoyl]pyrrolidin-2-yl]carbonylamino]methyl]-phenoxy-phosphinous acid
2
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
3
2
SODIUM IONSODIUM ION
4
1
PHOSPHATE IONPHOSPHATE ION
5
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303