6T7P: human plasmakallikrein protease domain in complex with active site directed inhibitor

PDB ID: 6T7PDownload
MMDB ID: 189808
PDB Deposition Date: 2019/10/22
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 1.416  Å
Source Organism:
Similar Structures:
Biological Unit for 6T7P: monomeric; determined by author and by software (PISA)
Molecular Components in 6T7P
Label Count Molecule
Protein (1 molecule)
1
Plasma Kallikrein
(Gene symbol: KLKB1)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
1
GLUTATHIONEGLUTATHIONE
2
10
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
PHOSPHATE IONPHOSPHATE ION
4
1
GLYCEROLGLYCEROL
5
1
(2~{S},4~{R})-1-[[(3~{S})-3-azanyl-2,3-dihydro-1-benzofuran-6-yl]carbonyl]-~{N}-(3-chlorophenyl)-4-phenyl-pyrrolidine-2-carboxamide(2~{S},4~{R})-1-[[(3~{S})-3-azanyl-2,3-dihydro-1-benzofuran-6-yl]carbonyl]-~{N}-(3-chlorophenyl)-4-phenyl-pyrrolidine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303