6T7H: Crystal structure of Thrombin in complex with macrocycle N14-PR4-A

PDB ID: 6T7HDownload
MMDB ID: 193404
PDB Deposition Date: 2019/10/22
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.32  Å
Source Organism:
Similar Structures:
Biological Unit for 6T7H: dimeric; determined by author and by software (PISA)
Molecular Components in 6T7H
Label Count Molecule
Proteins (2 molecules)
1
Thrombin Light Chain
(Gene symbol: F2)
Molecule annotation
1
Thrombin Heavy Chain
(Gene symbol: F2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
(14S,17R)-14-(3-carbamimidamidopropyl)-3-(furan-2-ylmethyl)-5,12,15-tris(oxidanylidene)-19-thia-3,6,13,16-tetrazatricyclo[19.4.0.0^{6,10}]pentacosa-1(25),7,9,21,23-pentaene-17-carboxamide(14S,17R)-14-(3-carbamimidamidopropyl)-3-(furan-2-ylmethyl)-5,12,15-tris(oxidanylidene)-19-thia-3,6,13,16-tetrazatricyclo[19.4.0.0^{6,10}]pentacosa-1(25),7,9,21,23-pentaene-17-carboxamide
4
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303