6T6D: Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2149

PDB ID: 6T6DDownload
MMDB ID: 180937
PDB Deposition Date: 2019/10/18
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.56  Å
Source Organism:
Similar Structures:
Biological Unit for 6T6D: monomeric; determined by author
Molecular Components in 6T6D
Label Count Molecule
Protein (1 molecule)
1
Activin Receptor Type I
(Gene symbol: ACVR1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide
2
3
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303