6T57: Thrombin in Complex with a D-Phe-Pro-N-amidinopiperidine Derivative

PDB ID: 6T57Download
MMDB ID: 194602
PDB Deposition Date: 2019/10/15
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 1.57  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 6T57: trimeric; determined by author and by software (PISA)
Molecular Components in 6T57
Label Count Molecule
Proteins (3 molecules)
1
Prothrombin
Molecule annotation
1
Prothrombin
Molecule annotation
1
Hirudin Variant-2
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
1
PHOSPHATE IONPHOSPHATE ION
3
2
SODIUM IONSODIUM ION
4
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
5
1
(2~{S})-1-[(2~{R})-2-azanyl-3-phenyl-propanoyl]-~{N}-[(1-carbamimidoylpiperidin-4-yl)methyl]pyrrolidine-2-carboxamide(2~{S})-1-[(2~{R})-2-azanyl-3-phenyl-propanoyl]-~{N}-[(1-carbamimidoylpiperidin-4-yl)methyl]pyrrolidine-2-carboxamide
6
1
trifluoroacetic acidtrifluoroacetic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303