6T4Y: ROR(gamma)t ligand binding domain in complex with 25-hydroxycholesterol and allosteric ligand MRL871

PDB ID: 6T4YDownload
MMDB ID: 194595
PDB Deposition Date: 2019/10/15
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 6T4Y: monomeric; determined by author and by software (PISA)
Molecular Components in 6T4Y
Label Count Molecule
Protein (1 molecule)
1
Nuclear Receptor Ror-gamma
(Gene symbol: RORC)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
25-HYDROXYCHOLESTEROL25-HYDROXYCHOLESTEROL
2
1
4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-1H-indazol-3-yl}benzoic acid4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-1H-indazol-3-yl}benzoic acid
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303