6T4W: ROR(gamma)t ligand binding domain in complex with 20-alpha-hydroxycholesterol and allosteric ligand Glenmark

PDB ID: 6T4WDownload
MMDB ID: 194593
PDB Deposition Date: 2019/10/15
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 1.71  Å
Source Organism:
Similar Structures:
Biological Unit for 6T4W: monomeric; determined by author and by software (PISA)
Molecular Components in 6T4W
Label Count Molecule
Protein (1 molecule)
1
Nuclear Receptor Ror-gamma
(Gene symbol: RORC)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
GLYCEROLGLYCEROL
2
1
4-[1-[2,6-bis(chloranyl)phenyl]carbonyl-5-methyl-thieno[3,2-c]pyrazol-3-yl]benzoic acid4-[1-[2,6-bis(chloranyl)phenyl]carbonyl-5-methyl-thieno[3,2-c]pyrazol-3-yl]benzoic acid
3
1
(3alpha,8alpha)-cholest-5-ene-3,20-diol(3alpha,8alpha)-cholest-5-ene-3,20-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303