6T41: CDK8/Cyclin C in complex with N-(4-chlorobenzyl)isoquinolin-4-amine

PDB ID: 6T41Download
MMDB ID: 182783
PDB Deposition Date: 2019/10/11
Updated in MMDB: 2020/02
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 6T41: dimeric; determined by author and by software (PISA)
Molecular Components in 6T41
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 8
(Gene symbol: CDK8)
Molecule annotation
1
Cyclin-c
(Gene symbol: CCNC)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
~{N}-[(4-chlorophenyl)methyl]quinazolin-4-amine~{N}-[(4-chlorophenyl)methyl]quinazolin-4-amine
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
5
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303