6T3B: Crystal structure of PI3Kgamma with a dihydropurinone inhibitor (compound 4)

PDB ID: 6T3BDownload
MMDB ID: 182781
PDB Deposition Date: 2019/10/10
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 3.01  Å
Source Organism:
Similar Structures:
Biological Unit for 6T3B: monomeric; determined by author and by software (PISA)
Molecular Components in 6T3B
Label Count Molecule
Protein (1 molecule)
1
Phosphatidylinositol 4,5-bisphosphate 3-kinase Catalytic Subunit Gamma Isoform
(Gene symbol: PIK3CG)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[(4-methoxy-2-methyl-phenyl)amino]-7-methyl-9-(4-oxidanylcyclohexyl)purin-8-one2-[(4-methoxy-2-methyl-phenyl)amino]-7-methyl-9-(4-oxidanylcyclohexyl)purin-8-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303