6T2W: Crystal structure of the CSF1R kinase domain with a dihydropurinone inhibitor (compound 4)

PDB ID: 6T2WDownload
MMDB ID: 182780
PDB Deposition Date: 2019/10/9
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6T2W: monomeric; determined by author and by software (PISA)
Molecular Components in 6T2W
Label Count Molecule
Protein (1 molecule)
1
Macrophage Colony-stimulating Factor 1 Receptor
(Gene symbol: CSF1R)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-[(4-methoxy-2-methyl-phenyl)amino]-7-methyl-9-(4-oxidanylcyclohexyl)purin-8-one2-[(4-methoxy-2-methyl-phenyl)amino]-7-methyl-9-(4-oxidanylcyclohexyl)purin-8-one
2
4
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303