6T2K: Furano[2,3-d]prymidine amides as Notum inhibitors

PDB ID: 6T2KDownload
MMDB ID: 182777
PDB Deposition Date: 2019/10/8
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 1.38  Å
Source Organism:
Similar Structures:
Biological Unit for 6T2K: monomeric; determined by author and by software (PISA)
Molecular Components in 6T2K
Label Count Molecule
Protein (1 molecule)
1
Palmitoleoyl-protein Carboxylesterase Notum
(Gene symbol: NOTUM)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
5
SULFATE IONSULFATE ION
2
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
3
1
2-(6-chloranyl-7-cyclopropyl-thieno[3,2-d]pyrimidin-4-yl)sulfanylethanoic acid2-(6-chloranyl-7-cyclopropyl-thieno[3,2-d]pyrimidin-4-yl)sulfanylethanoic acid
4
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303