6T2F: Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions

PDB ID: 6T2FDownload
MMDB ID: 183567
PDB Deposition Date: 2019/10/8
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.09  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6T2F: dimeric; determined by author and by software (PISA)
Molecular Components in 6T2F
Label Count Molecule
Proteins (2 molecules)
1
E3 Ubiquitin-protein Ligase Mdm2
Molecule annotation
1
Mdm2 in Complex With Gar300-am
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-(methylamino)-~{N}-[[3-[[2-(methylamino)ethanoylamino]methyl]phenyl]methyl]ethanamide2-(methylamino)-~{N}-[[3-[[2-(methylamino)ethanoylamino]methyl]phenyl]methyl]ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303