6SWN: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH iBET-BD1 (GSK778)

PDB ID: 6SWNDownload
MMDB ID: 192697
PDB Deposition Date: 2019/9/22
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.28  Å
Source Organism:
Similar Structures:
Biological Unit for 6SWN: monomeric; determined by author and by software (PISA)
Molecular Components in 6SWN
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
GLUTAMIC ACIDGLUTAMIC ACID
2
1
4-[2-(methoxymethyl)-1-[(1~{R})-1-phenylethyl]-8-[[(3~{S})-pyrrolidin-3-yl]methoxy]imidazo[4,5-c]quinolin-7-yl]-3,5-dimethyl-1,2-oxazole4-[2-(methoxymethyl)-1-[(1~{R})-1-phenylethyl]-8-[[(3~{S})-pyrrolidin-3-yl]methoxy]imidazo[4,5-c]quinolin-7-yl]-3,5-dimethyl-1,2-oxazole
3
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303